A mutation in the BRCA2 gene can hinder its ability to repair DNA, leading to genetic changes that can cause cancer. Individuals with [BRCA2 mutations](https://) have a significantly higher risk of developing breast, ovarian, prostate, and pancreatic cancers compared to those without the mutation. Women with a BRCA2 mutation have a 45-69% chance of developing breast cancer by age 70, whereas the risk for ovarian cancer is approximately 11-17%.
