Cancer can have a profound impact on excretory organs such as the kidneys, liver, and lungs. Tumors in these organs can directly impair their function, leading to reduced efficiency in waste removal. Additionally, cancer treatments like chemotherapy can cause nephrotoxicity or hepatotoxicity, further complicating excretory functions. For instance, kidney cancer can lead to a decline in renal function, affecting how the body filters and excretes waste products.