Treatment of shingles in cancer patients typically involves antiviral medications such as acyclovir, valacyclovir, or famciclovir, which are most effective when started within 72 hours of rash onset. Pain management is also a critical component of treatment, often requiring medications such as opioids, anticonvulsants, or antidepressants to manage severe pain. Coordination with oncology teams is essential to ensure that shingles treatment does not interfere with ongoing cancer therapies.