How Does Cancer Treatment Contribute to Peripheral Edema?
Various cancer treatments can contribute to peripheral edema. For instance, surgery to remove lymph nodes can disrupt normal lymphatic drainage, leading to fluid accumulation. Radiation therapy can cause inflammation and fibrosis, impairing lymphatic flow. Certain chemotherapy drugs may cause fluid retention either directly or indirectly by affecting kidney function. Hormonal therapies and steroids can also play a role in causing edema.