How Does Combined Use of Tobacco and Alcohol Affect Cancer Risk?
The combined use of tobacco and alcohol has a synergistic effect, meaning the risk of developing cancer is significantly higher when both substances are used together compared to each alone. This is particularly evident in cancers of the mouth, throat, and esophagus. The combined use exacerbates the damage to the cells, making it more difficult for the body to repair DNA damage and increasing the likelihood of cancerous mutations.
