How Does Gene Ontology Assist in Personalized Cancer Therapy?
In personalized cancer therapy, Gene Ontology helps in stratifying patients based on the functional annotations of their tumor genomes. By understanding the specific biological processes and molecular functions altered in a patient's cancer, clinicians can tailor treatments that target those particular disruptions. For instance, if a patient's cancer is characterized by defects in DNA repair mechanisms, therapies targeting these pathways can be selected.
