Hopelessness can have a profound impact on both the psychological and physical well-being of cancer patients. Research indicates that feelings of hopelessness are associated with poorer [mental health](#) outcomes, including depression and anxiety. Additionally, hopelessness can lead to a decreased motivation to adhere to treatment regimens, which can negatively affect [treatment outcomes](#). There is also evidence to suggest that hopelessness may affect the body's ability to fight cancer, potentially influencing [disease progression](#).