How Does Irinotecan Interact with Other Medications?
Irinotecan can interact with several other medications, which can either increase its toxicity or reduce its effectiveness. For example, drugs like ketoconazole can increase the levels of irinotecan in the blood, while anticonvulsants such as phenytoin can decrease its levels. It's crucial for patients to inform their healthcare providers about all medications they are taking, including over-the-counter drugs and supplements.