hemochromatosis

How Does Iron Contribute to Cancer Development?

Iron plays a crucial role in various cellular processes, including DNA synthesis and repair. However, excessive iron can generate free radicals through the Fenton reaction, leading to oxidative stress. This oxidative stress can cause DNA damage, promoting mutations and the development of cancer. Additionally, iron can facilitate the proliferation of cancer cells by supplying the necessary nutrients and promoting angiogenesis, the formation of new blood vessels that feed tumors.

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