Panobinostat works by blocking the activity of histone deacetylases, which leads to an accumulation of acetylated histones and proteins. This accumulation alters the expression of multiple genes involved in cell cycle regulation, apoptosis, and angiogenesis, ultimately inhibiting the proliferation of cancer cells and inducing apoptosis or programmed cell death. By interfering with the cell cycle, panobinostat can slow down or stop the growth of cancer cells.
