How Does PhosphoSitePlus Enhance Targeted Cancer Therapies?
Targeted cancer therapies aim to disrupt specific molecular pathways that are crucial for cancer cell survival and proliferation. By offering a detailed map of phosphorylation sites, PhosphoSitePlus helps in identifying potential targets for kinase inhibitors and other targeted therapies. For instance, the database can be used to find key phosphorylation sites on oncogenes or tumor suppressors, facilitating the development of drugs that specifically target these sites.
