What is Genomic Instability and How is it Linked to Cancer?
Genomic instability refers to an increased tendency of the genome to acquire mutations. This instability is a hallmark of many cancers and can result from defects in DNA repair mechanisms, chromosomal segregation errors, or oxidative stress. Genomic instability accelerates the mutation rate, increasing the likelihood of acquiring mutations in critical genes that control cell growth and division, thereby promoting cancer progression.