How Do Tumor Suppressor Genes and Oncogenes Interact?
Tumor suppressor genes and oncogenes are crucial for the regulation of cell growth and division. Tumor suppressor genes, like TP53, help to prevent uncontrolled cell growth by initiating cell cycle arrest, DNA repair, or apoptosis. Oncogenes, on the other hand, promote cell proliferation and survival. Mutations that inactivate tumor suppressor genes or activate oncogenes can disrupt the balance between cell growth and death, leading to cancer.
