How has the understanding of the tumor microenvironment evolved?
The tumor microenvironment, comprising various cell types, signaling molecules, and extracellular matrix components, plays a crucial role in cancer progression and treatment resistance. Recent research has focused on disrupting the supportive interactions within the microenvironment to hinder tumor growth. Targeting cancer-associated fibroblasts, immune cells, and angiogenesis are some of the strategies being explored.
