The procedure for using a biopsy needle varies depending on the type of biopsy being performed. Generally, the skin over the area to be biopsied is cleaned and numbed with local anesthesia. The needle is then inserted through the skin and into the target tissue. For image-guided biopsies, techniques like ultrasound, CT scans, or MRI are used to precisely guide the needle to the right location. Once the needle is in place, a small sample of tissue is extracted and sent to a laboratory for analysis.