The administration of aggressive chemotherapy can vary, but it often includes: - __Intravenous (IV) Infusion__: Delivered directly into the bloodstream through a vein. This can be done in a hospital setting. - __Oral Chemotherapy__: High-dose chemotherapy drugs taken by mouth. - __Intrathecal Injection__: Administered into the cerebrospinal fluid to treat __cancers of the central nervous system__. - __Continuous Infusion__: Delivered over a prolonged period using a pump.