Implementation of block randomization involves several steps:
Define the block size: Researchers decide on the number of participants per block. Common block sizes are 4, 6, or 8 participants. Generate randomization sequences: Within each block, participants are randomly assigned to different treatment groups. This can be done using computer-generated randomization lists. Enroll participants: As participants enroll in the trial, they are assigned to a treatment group based on the predefined randomization sequence for their block.
