Detection of chimerism involves several molecular techniques. The most common methods include: - Short Tandem Repeat (STR) Analysis: This method analyzes specific regions of DNA that vary highly among individuals. - Fluorescence In Situ Hybridization (FISH): This technique uses fluorescent probes to detect DNA sequences. - Polymerase Chain Reaction (PCR): PCR can amplify specific DNA sequences to identify the presence of multiple cell lines.