How Is Electron Microscopy Complemented by Other Techniques?
EM is often used in conjunction with other techniques to provide a more comprehensive understanding of cancer. For example:
Light Microscopy: While EM offers higher resolution, light microscopy can provide a broader context, making it easier to locate regions of interest for further EM analysis. Molecular Biology Techniques: Techniques such as PCR and Western blotting can offer insights into the genetic and protein expression profiles of cancer cells, complementing the structural data from EM. Cryo-Electron Microscopy: This advanced form of EM allows for the observation of specimens in a near-native state without the need for extensive preparation, making it ideal for studying protein complexes and viruses related to cancer.
