Detecting heterogeneity in cancer involves multiple advanced techniques.
- Genomic Sequencing: This technique identifies genetic mutations and variations within the tumor. Advances in next-generation sequencing (NGS) allow for high-resolution analysis of the tumor’s genetic landscape.
- Imaging Techniques: Advanced imaging technologies like PET scans, MRI, and CT scans help in visualizing the structural and functional diversity within tumors.
- Biopsies and Liquid Biopsies: Traditional biopsies provide tissue samples from specific parts of the tumor, but they may miss heterogeneous regions. Liquid biopsies, which analyze circulating tumor DNA (ctDNA) in the blood, offer a more comprehensive overview of the tumor’s genetic diversity.
