What are Multidrug Resistance Associated Proteins (MRPs)?
Multidrug Resistance Associated Proteins (MRPs) are a family of transport proteins that belong to the ATP-binding cassette (ABC) transporter superfamily. These proteins play a crucial role in the efflux of various substrates, including drugs, out of cells. MRPs contribute significantly to multidrug resistance (MDR) in cancer, which is one of the major challenges in effective cancer treatment.
