How is Post-Transcriptional Regulation Altered in Cancer?
In cancer, post-transcriptional regulation is frequently dysregulated. This can occur through various mechanisms including alterations in the expression or function of RNA-binding proteins (RBPs), non-coding RNAs like microRNAs (miRNAs), and changes in mRNA splicing patterns. These alterations can lead to the aberrant expression of oncogenes and tumor suppressor genes, contributing to cancer progression.
