The comprehensive data from TCGA has been instrumental in several key areas of cancer research:
Identification of driver mutations: Researchers use TCGA data to pinpoint genetic mutations that play a crucial role in cancer development and progression. Understanding tumor heterogeneity: TCGA helps in revealing the complexity and diversity of tumor cells within a single patient, as well as among different patients. Developing targeted therapies: By identifying specific genetic alterations, researchers can develop therapies that target those changes, improving treatment efficacy. Biomarker discovery: TCGA data is used to find biomarkers that can predict disease prognosis, response to treatment, and risk of recurrence.