The procedure involves the following steps: 1. Sample Preparation: Cells or tissue sections are prepared on slides. 2. Denaturation: The DNA on the slides is denatured to single strands by applying heat or chemicals. 3. Hybridization: Fluorescently labeled probes specific to telomere sequences are applied to the slides. These probes hybridize with the telomere regions. 4. Washing: Excess probes are washed away. 5. Visualization: The slides are examined under a fluorescence microscope. The fluorescent signals indicate the locations of the telomeres.
