What are the Clinical Applications of Telomere Specific FISH in Cancer?
Telomere Specific FISH has several clinical applications: - Diagnosis: It can be used to diagnose certain cancers by identifying characteristic telomere alterations. - Prognosis: Telomere length and integrity can provide prognostic information. Shorter telomeres and telomere abnormalities are often associated with more aggressive cancers and poorer outcomes. - Therapeutic Targeting: Understanding telomere dynamics in cancer cells can aid in the development of telomerase inhibitors and other targeted therapies.