How is the Actin Cytoskeleton Regulated in Cancer Cells?
The regulation of the actin cytoskeleton in cancer cells involves various signaling pathways, including the Rho family of GTPases, such as RhoA, Rac1, and Cdc42. These molecules modulate actin polymerization and cytoskeletal reorganization. Aberrant activation of these pathways can lead to increased cell motility and invasion.