How is the Efficacy of Combination Strategies Evaluated?
Efficacy is typically evaluated through clinical trials, which can be designed to test:
1. Safety and Tolerability: Phase I trials focus on determining the safe dosage ranges and identifying side effects. 2. Efficacy: Phase II trials assess how well the combination works against the cancer. 3. Comparison to Standard Treatments: Phase III trials compare the new combination strategy to the current standard of care, assessing survival rates, progression-free survival, and quality of life.
