B Cell Engagers, also known as Bispecific T-cell Engagers (BiTEs), are a type of targeted immunotherapy designed to harness the body's immune system to fight cancer. These agents work by linking cancer cells to T cells, specifically bringing together a T cell and a cancer cell to facilitate the T cell-mediated killing of the cancer cell. They are engineered proteins that have two binding sites: one binds to a specific antigen on cancer cells, and the other binds to CD3 on T cells.
