BRCA1 (Breast Cancer 1) and MLH1 (MutL Homolog 1) are two critical genes involved in maintaining the integrity of the human genome. BRCA1 is primarily known for its role in DNA repair, specifically in the repair of double-strand breaks. MLH1, on the other hand, is a key player in the mismatch repair (MMR) system, which corrects errors that occur during DNA replication.