What Are Checkpoint Inhibitors and How Do They Work?
Checkpoint inhibitors are a type of immunotherapy that block checkpoint proteins from binding with their partner proteins. This prevents the "off" signal from being sent, allowing T-cells to kill cancer cells. Common checkpoint inhibitors target proteins such as PD-1, PD-L1, and CTLA-4. These inhibitors have shown significant success in treating various cancers by reactivating the immune response against tumor cells.
