Drug Screening: Organoids can be used for high-throughput
drug screening to identify potential therapeutics. Because they mimic real tumors, they provide more accurate data on how drugs will perform in clinical settings.
Modeling Cancer Genetics: Organoids can be genetically engineered to study the impact of specific mutations, helping scientists understand the
genetic basis of cancer and identify novel targets for therapy.
Understanding Tumor Heterogeneity: Tumors are often composed of a mix of different cell types. Organoids can capture this
heterogeneity, allowing researchers to study how different cell populations within a tumor interact and contribute to disease progression.
Personalized Therapy: Patient-derived organoids can be used to test the efficacy of different treatments, helping clinicians select the most effective therapeutic strategies for individual patients, also known as
precision oncology.
Studying Metastasis: Organoids can be used to model the process of metastasis, providing insights into how cancer cells spread from the primary tumor to other parts of the body.