pan cancer analysis of whole genomes (pcawg)

What are Mutational Signatures and Their Significance?

Mutational signatures are patterns of mutations that arise due to specific [mutagenic processes](https://), such as exposure to UV light or tobacco smoke. PCAWG has identified numerous mutational signatures, helping to link specific environmental exposures and biological processes to cancer development. Understanding these signatures can aid in identifying the causes of cancer and in developing prevention strategies.

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