What are Some Challenges in Exploiting Surface Sensitivity?
Despite its potential, there are several challenges in exploiting surface sensitivity for cancer diagnosis and treatment:
Heterogeneity: Cancer cells within the same tumor can exhibit significant variability in their surface markers, complicating the development of uniform diagnostic and therapeutic strategies. Resistance: Cancer cells can develop resistance to targeted therapies by altering their surface markers or through other mechanisms, necessitating the continuous development of new treatments. Detection Limits: The sensitivity and specificity of detection techniques need to be high enough to identify cancer cells at early stages, which can be challenging.
