mechanisms of apoptosis

What Are Some Challenges in Targeting Apoptosis in Cancer Therapy?

One of the major challenges in targeting apoptosis in cancer therapy is the heterogeneity of tumors. Different cancers and even different cells within the same tumor may have distinct mechanisms for evading apoptosis. Additionally, targeting apoptosis can sometimes lead to resistance or adverse side effects, necessitating the need for combination therapies and personalized treatment approaches.

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