What are Some Challenges in Using Gencode for Cancer Research?
Despite its vast utility, there are several challenges in using Gencode for cancer research. One major challenge is the complexity and heterogeneity of cancer genomes. Different types of cancer, and even different tumors within the same type, can have vastly different genetic profiles. Another challenge is the need for advanced computational tools and expertise to analyze the large datasets provided by Gencode. Additionally, integrating Gencode data with other types of biological data, such as epigenetic and proteomic data, remains a significant hurdle.
