What Are Some Examples of Approved Drug Conjugates?
Several ADCs have been approved for clinical use. Examples include:
- Brentuximab vedotin: Approved for the treatment of Hodgkin lymphoma and systemic anaplastic large cell lymphoma. - Trastuzumab emtansine (T-DM1): Used for HER2-positive metastatic breast cancer. - Inotuzumab ozogamicin: Approved for relapsed or refractory B-cell precursor acute lymphoblastic leukemia.