What are Some Examples of Biomarker Driven Trials?
One well-known example is the use of the HER2 biomarker in breast cancer. Patients with HER2-positive tumors are often treated with targeted therapies like trastuzumab. Another example is the use of EGFR mutations in non-small cell lung cancer, where patients with these mutations may receive tyrosine kinase inhibitors such as erlotinib or gefitinib.