What are Some Examples of Differentiation Antigens?
Several differentiation antigens have been identified and studied in various cancers. For instance, Melanoma-associated antigen (MAGE) is a well-known differentiation antigen expressed in melanomas but not in normal tissues except for the testis. Similarly, Carcinoembryonic antigen (CEA) is highly expressed in colorectal cancers and can serve as a diagnostic marker. Another example is Prostate-specific antigen (PSA), widely used in the detection and monitoring of prostate cancer.
