What are some examples of oncogenic and tumor-suppressive miRNAs?
Oncogenic miRNAs, also known as oncomiRs, promote cancer by targeting tumor suppressor genes. Examples include miR-21, which targets PTEN, and miR-155, which targets SOCS1. Tumor-suppressive miRNAs inhibit cancer by targeting oncogenes. Examples include let-7, which targets RAS, and miR-34, which targets MYC and BCL2.
