What Are Some Key Findings from Boyden Chamber Assays in Cancer Research?
Several groundbreaking studies have utilized the Boyden chamber assay to uncover critical insights into cancer biology. For instance, the identification of signaling pathways such as PI3K/AKT and MAPK that regulate cell migration has been facilitated by this assay. Additionally, it has helped in understanding the role of epithelial-mesenchymal transition (EMT) in cancer metastasis, highlighting key molecular changes that enable cancer cells to become more migratory and invasive.
