What Are Some Key Genomic Alterations Identified in Cancer?
Several key genomic alterations have been identified in cancer, including mutations in oncogenes (e.g., KRAS, BRAF), tumor suppressor genes (e.g., TP53, RB1), and genes involved in DNA repair (e.g., BRCA1, BRCA2). These genetic changes can lead to uncontrolled cell growth, resistance to cell death, and other hallmarks of cancer.
