What Are Some Key Pathways Involved in Cancer According to Reactome?
Several critical pathways are frequently altered in cancer, according to Reactome. These include the PI3K-Akt signaling pathway, the MAPK/ERK pathway, and the p53 pathway. The PI3K-Akt pathway is involved in cell growth and survival, the MAPK/ERK pathway regulates cell division, and the p53 pathway is crucial for DNA damage repair and apoptosis. Deregulation of these pathways can lead to uncontrolled cell proliferation and resistance to cell death, hallmarks of cancer.
