scanning electron microscopy (sem)

What Are Some Limitations of SEM in Cancer Research?

Despite its advantages, SEM has some limitations:
Sample Preparation: Samples often require extensive preparation, including dehydration and coating with conductive materials, which can alter their natural state.
Limited Penetration Depth: SEM primarily examines surface features and has limited capability to visualize internal structures of thick samples.
Cost and Accessibility: SEM equipment is expensive and requires specialized facilities and trained personnel, making it less accessible for some research settings.

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