What are the Advantages of Using Aptamers Over Antibodies?
Aptamers offer several advantages over traditional antibodies. First, they are smaller and can penetrate tissues more easily, enhancing their ability to reach tumor cells. Second, aptamers are synthesized chemically, which allows for high reproducibility and scalability. Unlike antibodies, which require biological systems for production, aptamers can be generated in vitro, reducing the risk of batch-to-batch variability and contamination. Third, aptamers are less likely to elicit immune responses, making them safer for repeated administration. Finally, aptamers can be easily modified to improve their stability, binding affinity, and specificity, providing a versatile platform for cancer diagnosis and therapy.
