What are the Advantages of Using Prodrugs in Cancer Therapy?
Reduced Toxicity: By limiting the activation of the drug to cancerous tissues, prodrugs can significantly reduce the adverse effects associated with chemotherapy. Improved Solubility and Absorption: Prodrugs can be designed to enhance the physicochemical properties of the active drug, improving its solubility and absorption. Increased Targeting: Prodrugs can be engineered to exploit specific characteristics of tumors, providing targeted delivery that enhances therapeutic efficacy. Enhanced Stability: Prodrugs often offer improved chemical and metabolic stability, increasing the shelf-life and bioavailability of the drug.
