Y2H screening offers several advantages in cancer research:
High throughput: Large libraries of potential interacting proteins can be screened simultaneously. Versatility: It can be adapted to study various types of proteins, including membrane-bound and soluble proteins. Cost-effective: Compared to other interaction mapping techniques, Y2H is relatively inexpensive. Functional interactions: It screens for interactions in a eukaryotic context, increasing the relevance of the findings.
