Other aromatase inhibitors, such as anastrozole and exemestane, can be used as alternatives to letrozole. Additionally, selective estrogen receptor modulators (SERMs) like tamoxifen may be prescribed, especially for premenopausal women or those who cannot tolerate aromatase inhibitors. The choice of therapy depends on several factors, including the patient's menopausal status, the specific characteristics of the cancer, and the patient's overall health and preferences.
