What Are the Applications of iRegulon in Cancer Studies?
iRegulon has several applications in cancer research, including:
Identifying Master Regulators: iRegulon can highlight master regulators that control the expression of numerous genes involved in cancer, helping to understand the core regulatory circuits. Predicting Drug Targets: By identifying key TFs that drive cancer progression, researchers can target these TFs or their pathways for therapeutic intervention. Understanding Tumor Heterogeneity: iRegulon can be used to study the differences in regulatory networks between various cancer subtypes or even within different regions of the same tumor. Biomarker Discovery: The tool can help discover potential biomarkers for cancer diagnosis, prognosis, and treatment response by identifying genes regulated by specific TFs.
