- Increased Surgical Success: Smaller tumors are easier to remove and reduce the risk of leaving behind cancerous tissue. - Improving Survival Rates: By addressing both the primary tumor and potential micrometastatic disease, it can improve long-term survival. - Better Cosmetic Outcomes: In cancers like breast cancer, it can allow for less extensive surgery, preserving the appearance and function of the breast. - Early Response Evaluation: It provides an early indication of how the cancer responds to treatment, guiding further therapy decisions.