What are the Challenges and Limitations of FA in Cancer Imaging?
Despite its potential, FA has several limitations and challenges:
Complexity of Interpretation: FA values can be influenced by various factors, making interpretation complex. For instance, low FA values could result from both tumor infiltration and edema. Technical Variability: Variations in imaging protocols, scanner types, and post-processing techniques can affect FA measurements, leading to potential inconsistencies. Sensitivity to Motion: Patient motion during imaging can significantly impact FA measurements, necessitating high levels of patient compliance and potentially multiple scans. Limited Availability: Advanced imaging techniques like DTI and FA are not uniformly available across all healthcare settings, limiting their widespread application.
